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Examples:     mTOR regulators     Autophagy-Lysosomal    
1 gene found on 1: RRAGC

TFEB GENE PERTURBATION

TIME SERIES (GSE98247)      GP Score        NETWORK      TFEB Target          KEGG Autophagy    
Fold Change (log2t/t0) COLOR LEGEND

■ RRAGC
GENE EXPRESSION PROFILE      FDR             Background Legend  
Genesymbol Experiment FDR Signed Ratio
RRAGCTFEB HeLa - OE (GSE16267) 0.0015841691.676950057
RRAGCTFEB-GFP HeLa - OE (GSE73055) 1.44e-06-1.362631813
RRAGCTFEB-3xFLAG HeLa - OE (GSE73054) 1.05e-05-1.396936467

BIOINFORMATIC PREDICTION OF BINDING SITES

Homo Sapiens (hg19)        Upstream      Downstream      PWM Score       
Genesymbol Score Binding Site Chrom Start End Strand TSS Position Promoter Sequence View
RRAGC0.9741982GGCACGTGACchr13932554939325558--62PromoterIGV

EXPERIMENTAL ChIP-seq

ChIP-seq HEK-293 (GSE98246)      Upstream      Downstream       
Genesymbol Chrom Start End TSS Position View
RRAGCchr139325474393260570IGV
ChIP-seq HeLa (Palmieri et al., HMG 2011 - ChIP-seq Palmieri HMG )
Genesymbol Chrom Start End TSS Position View
RRAGCchr139325313393258530IGV




Copyright © 2020 Tigem. Designed by Diego Carrella in collaboration with Rossella De Cegli
Data produced by Ballabio’s and di Bernardo’s lab

Please cite: Rossella De Cegli, Diego Carrella, Diletta Siciliano, Gennaro Gambardella, Gennaro Napolitano, Chiara Di Malta, Andrea Ballabio & Diego di Bernardo (2022) TFEBexplorer: An integrated tool to study genes regulated by the stress-responsive Transcription Factor EB, Autophagy Reports, 1:1, 295-305, DOI: 10.1080/27694127.2022.2097822

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